Today we were told that only four bottles of a combination arv were in stock and, at our current pace of prescribing, the supply would be done by next week. An hiv treatment interruption—even by hours—can lead to viral resistance and end the capacity of drugs to beat the virus, not only for the individual whose continuity of arvs is broken but beyond, filtering through to sexual contacts newly infected with now-drug-resistant hiv.
January 2, 2005
January 5, 2005
Some signs of victorious battles . . . twenty-nine-year-old woman, 46.5 kg , cd4* count of 411 (almost normal) and a hemoglobin† of 9.4 (normal is 12 but this is great for here); my colleague Dr. Bob Birnbaum exclaims “she is rocking” and so she is. Saw in follow-up a twenty-seven-year-old woman who we treated for a presumptive pcp‡ on Dec. 22, then gasping at 48 breaths/minute with an exercise-class pulse of 144/min—now breathing at 16/min and pulse at 108/min. Her hemoglobin, at 7.7, will always give her a fast pulse but as she says, “I can breathe.”
*cd4—The immune system’s critical cells that hiv attacks
†Hemoglobin—Oxygen-carrying molecules of our bodies
‡pcp—Killer aids pneumonia
January 9, 2005
While climbing the 180-metre mountain behind my house this a.m. with Bob and Russell, passing rondavals, gardens, massive aloe trees, cattle in pasture, brick huts, roofs held down by rocks, always greeted by smiles, hellos and some giggles, guided at times by young barefoot boys to the safest path, we were discussing hiv resistance. Bob said if the arvs are not available this week it means resistance, and I agreed it would be disaster for Lesotho and he said “No, resistance for the world.” He is right. Then horrible thoughts came . . . so what, Lesotho dies with aids and without arvs and without resistance, or it dies with aids and with an interrupted supply of arvs and no infrastructure and arv resistance. So what? Matters not to a fifteen-to-forty-nine-year-old generation who will fade away anyway. hiv and hiv resistance could be halted if hiv was engaged as war is engaged. In the meantime Lesotho and the patients we see have nothing to lose, may even gain a few years (which is a lot here and they know it).








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